Association of HLA-A3 and HLA-B14 antigens

نویسندگان

  • M. SIMON
  • M. BOUREL
  • R. FAUCHET
  • B. GENETET
چکیده

The frequency of HLA-A3 and HLA-B14 antigens was significantly higher in a series of 51 patients with idiopathic haemochromatosis than in a control group, being respectively 78-4 versus 27 0% and 25 5 versus 3 4 %. This finding strongly supports the suggestion that idiopathic haemochromatosis is a genetic disease and suggests that the gene(s) responsible for the disease may be linked to the histocompatibility genes.

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Association of HLA-A3 and HLA-B14 antigens with idiopathic haemochromatosis.

The frequency of HLA-A3 and HLA-B14 antigens was significantly higher in a series of 51 patients with idiopathic haemochromatosis than in a control group, being respectively 78-4 versus 27-0% and 25-5 versus 3-4%. This finding strongly supports the suggestion that idiopathic haemochromatosis is a genetic disease and suggests that the gene(s) responsible for the disease may be linked to the hist...

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تاریخ انتشار 2006